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In silico investigation into dendritic cell regulation of CD8Treg mediated killing of Th1 cells in murine experimental autoimmune encephalomyelitis

BACKGROUND: Experimental autoimmune encephalomyelitis has been used extensively as an animal model of T cell mediated autoimmunity. A down-regulatory pathway through which encephalitogenic CD4Th1 cells are killed by CD8 regulatory T cells (Treg) has recently been proposed. With the CD8Treg cells bei...

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Detalles Bibliográficos
Autores principales:	Williams, Richard A, Greaves, Richard, Read, Mark, Timmis, Jon, Andrews, Paul S, Kumar, Vipin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633023/ https://www.ncbi.nlm.nih.gov/pubmed/23734666 http://dx.doi.org/10.1186/1471-2105-14-S6-S9

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