Pharmacokinetic and pharmacodynamic characterization of a new formulation containing synergistic proportions of interferons alpha-2b and gamma (HeberPAG®) in patients with mycosis fungoides: an open-label trial

BACKGROUND: The synergistic combination of interferon (IFN) alpha-2b and IFN gamma results in more potent in vitro biological effects mediated by both IFNs. The aim of this investigation was to evaluate by first time the pharmacokinetics and pharmacodynamics of this combination in patients with myco...

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Detalles Bibliográficos
Autores principales: García-Vega, Yanelda, García-García, Idrian, Collazo-Caballero, Sonia E, Santely-Pravia, Egla E, Cruz-Ramírez, Alieski, Tuero-Iglesias, Ángela D, Alfonso-Alvarado, Cristian, Cabrera-Placeres, Mileidys, Castro-Basart, Nailet, Duncan-Roberts, Yaquelín, Carballo-Treto, Tania I, Soto-Matos, Josanne, Izquierdo-Toledo, Yoandy, Vázquez-Blomquist, Dania, García-Iglesias, Elizeth, Bello-Rivero, Iraldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633053/
https://www.ncbi.nlm.nih.gov/pubmed/23272809
http://dx.doi.org/10.1186/2050-6511-13-20

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