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Nuclear Receptors as Drug Targets in Cholestatic Liver Diseases

Cholestatic liver diseases encompass a wide spectrum of disorders with different causes, resulting in impaired bile flow and accumulation of bile acids and other potentially hepatotoxic cholephils. The understanding of the molecular mechanisms of bile formation and cholestasis has recently improved...

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Detalles Bibliográficos
Autores principales: Halilbasic, Emina, Baghdasaryan, Anna, Trauner, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Health Sciences Division 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633080/
https://www.ncbi.nlm.nih.gov/pubmed/23540496
http://dx.doi.org/10.1016/j.cld.2012.12.001