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Gain-of-Function Mutations in the K(ATP) Channel (KCNJ11) Impair Coordinated Hand-Eye Tracking

BACKGROUND: Gain-of-function mutations in the ATP-sensitive potassium channel can cause permanent neonatal diabetes mellitus (PNDM) or neonatal diabetes accompanied by a constellation of neurological symptoms (iDEND syndrome). Studies of a mouse model of iDEND syndrome revealed that cerebellar Purki...

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Detalles Bibliográficos
Autores principales:	McTaggart, James S., Jenkinson, Ned, Brittain, John-Stuart, Greeley, Siri A. W., Hattersley, Andrew T., Ashcroft, Frances M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633835/ https://www.ncbi.nlm.nih.gov/pubmed/23626843 http://dx.doi.org/10.1371/journal.pone.0062646

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