The PI3K/AKT/mTOR Signaling Pathway Is Overactivated in Primary Aldosteronism

BACKGROUND: To date, the available non-invasive remedies for primary aldosteronism are not satisfactory in clinical practice. The phosphoinositide 3-kinase (PI3Ks)/protein kinase B (PKB or AKT)/mammalian target of rapamycin (mTOR) signaling pathway is essential for tumorigenesis and metastasis in ma...

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Detalles Bibliográficos
Autores principales: Su, Hengchuan, Gu, Yanyun, Li, Fengying, Wang, Qidi, Huang, Baoxing, Jin, Xiaolong, Ning, Guang, Sun, Fukang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633845/
https://www.ncbi.nlm.nih.gov/pubmed/23626817
http://dx.doi.org/10.1371/journal.pone.0062399

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