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Reduced Expression of miR-200 Family Members Contributes to Antiestrogen Resistance in LY2 Human Breast Cancer Cells
INTRODUCTION: The role of miRNAs in acquired endocrine-resistant breast cancer is not fully understood. One hallmark of tumor progression is epithelial-to-mesenchymal transition (EMT), characterized by a loss of cell adhesion resulting from reduced E-cadherin and increased cell mobility. miR-200 fam...
Autores principales: | Manavalan, Tissa T., Teng, Yun, Litchfield, Lacey M., Muluhngwi, Penn, Al-Rayyan, Numan, Klinge, Carolyn M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633860/ https://www.ncbi.nlm.nih.gov/pubmed/23626803 http://dx.doi.org/10.1371/journal.pone.0062334 |
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