Insulin Regulates Hypoxia-Inducible Factor-1α Transcription by Reactive Oxygen Species Sensitive Activation of Sp1 in 3T3-L1 Preadipocyte

Oxygen sensing transcription factor HIF-1 is activated due to accumulation of regulatory subunit HIF-1α by posttranslational stability mechanism during hypoxia or by several other stimuli even in normoxia. HIF-1α is also regulated by NF-kB mediated transcription mechanism. Reactive oxygen species (R...

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Detalles Bibliográficos
Autores principales: Biswas, Sudipta, Mukherjee, Reshmi, Tapryal, Nisha, Singh, Amit K., Mukhopadhyay, Chinmay K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633924/
https://www.ncbi.nlm.nih.gov/pubmed/23626778
http://dx.doi.org/10.1371/journal.pone.0062128

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