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Human S100A9 Protein Is Stabilized by Inflammatory Stimuli via the Formation of Proteolytically-Resistant Homodimers

S100A8 and S100A9 are Ca(2+)-binding proteins that are associated with acute and chronic inflammation and cancer. They form predominantly heterodimers even if there are data supporting homodimer formation. We investigated the stability of the heterodimer in myeloid and S100A8/S100A9 over-expressing...

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Detalles Bibliográficos
Autores principales: Riva, Matteo, He, Zhifei, Källberg, Eva, Ivars, Fredrik, Leanderson, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633927/
https://www.ncbi.nlm.nih.gov/pubmed/23626736
http://dx.doi.org/10.1371/journal.pone.0061832