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Human S100A9 Protein Is Stabilized by Inflammatory Stimuli via the Formation of Proteolytically-Resistant Homodimers
S100A8 and S100A9 are Ca(2+)-binding proteins that are associated with acute and chronic inflammation and cancer. They form predominantly heterodimers even if there are data supporting homodimer formation. We investigated the stability of the heterodimer in myeloid and S100A8/S100A9 over-expressing...
Autores principales: | Riva, Matteo, He, Zhifei, Källberg, Eva, Ivars, Fredrik, Leanderson, Tomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633927/ https://www.ncbi.nlm.nih.gov/pubmed/23626736 http://dx.doi.org/10.1371/journal.pone.0061832 |
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