Divergent Roles of Amino Acid Residues Inside and Outside the BB Loop Affect Human Toll-Like Receptor (TLR)2/2, TLR2/1 and TLR2/6 Responsiveness

TLR2 specifically recognizes a wide range of ligands by homodimerizing or heterodimerizing with TLR1 or TLR6. However, the molecular basis of the specific signalling transduction induced by TLR2 homodimerization or heterodimerization with TLR1 or TLR6 is largely unknown. In this study, we found thre...

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Detalles Bibliográficos
Autores principales: Qiu, Yuan, Ding, Yan, Zou, Lingyun, Tan, Zhangping, Liu, Taiping, Fu, Xiaolan, Xu, Wenyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634009/
https://www.ncbi.nlm.nih.gov/pubmed/23626692
http://dx.doi.org/10.1371/journal.pone.0061508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634009/
https://www.ncbi.nlm.nih.gov/pubmed/23626692
http://dx.doi.org/10.1371/journal.pone.0061508

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