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Xenobiotic-Induced Hepatocyte Proliferation Associated with Constitutive Active/Androstane Receptor (CAR) or Peroxisome Proliferator-Activated Receptor α (PPARα) Is Enhanced by Pregnane X Receptor (PXR) Activation in Mice

Xenobiotic-responsive nuclear receptors pregnane X receptor (PXR), constitutive active/androstane receptor (CAR) and peroxisome proliferator-activated receptor α (PPARα) play pivotal roles in the metabolic functions of the liver such as xenobiotics detoxification and energy metabolism. While CAR or...

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Detalles Bibliográficos
Autores principales:	Shizu, Ryota, Benoki, Satoshi, Numakura, Yuki, Kodama, Susumu, Miyata, Masaaki, Yamazoe, Yasushi, Yoshinari, Kouichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634023/ https://www.ncbi.nlm.nih.gov/pubmed/23626729 http://dx.doi.org/10.1371/journal.pone.0061802

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