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Designed Ankyrin Repeat Proteins: A New Approach to Mimic Complex Antigens for Diagnostic Purposes?

Inhibitory antibodies directed against coagulation factor VIII (FVIII) can be found in patients with acquired and congenital hemophilia A. Such FVIII-inhibiting antibodies are routinely detected by the functional Bethesda Assay. However, this assay has a low sensitivity and shows a high inter-labora...

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Detalles Bibliográficos
Autores principales:	Hausammann, Stefanie, Vogel, Monique, Kremer Hovinga, Johanna A., Lacroix-Desmazes, Sebastien, Stadler, Beda M., Horn, Michael P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634029/ https://www.ncbi.nlm.nih.gov/pubmed/23626669 http://dx.doi.org/10.1371/journal.pone.0060688

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