Enhanced Immune Response and Protective Effects of Nano-chitosan-based DNA Vaccine Encoding T Cell Epitopes of Esat-6 and FL against Mycobacterium Tuberculosis Infection

Development of a novel and effective vaccine against Mycobacterium tuberculosis (M.tb) is a challenging for preventing TB infection. In this study, a novel nanoparticle-based recombinant DNA vaccine was developed, which contains Esat-6 three T cell epitopes (Esat-6/3e) and fms-like tyrosine kinase 3...

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Detalles Bibliográficos
Autores principales: Feng, Ganzhu, Jiang, Qingtao, Xia, Mei, Lu, Yanlai, Qiu, Wen, Zhao, Dan, Lu, Liwei, Peng, Guangyong, Wang, Yingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634041/
https://www.ncbi.nlm.nih.gov/pubmed/23637790
http://dx.doi.org/10.1371/journal.pone.0061135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634041/
https://www.ncbi.nlm.nih.gov/pubmed/23637790
http://dx.doi.org/10.1371/journal.pone.0061135

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