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On the Power and the Systematic Biases of the Detection of Chromosomal Inversions by Paired-End Genome Sequencing
One of the most used techniques to study structural variation at a genome level is paired-end mapping (PEM). PEM has the advantage of being able to detect balanced events, such as inversions and translocations. However, inversions are still quite difficult to predict reliably, especially from high-t...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634047/ https://www.ncbi.nlm.nih.gov/pubmed/23637806 http://dx.doi.org/10.1371/journal.pone.0061292 |