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Lithium Inhibits Tumorigenic Potential of PDA Cells through Targeting Hedgehog-GLI Signaling Pathway

Hedgehog signaling pathway plays a critical role in the initiation and development of pancreatic ductal adenocarcinoma (PDA) and represents an attractive target for PDA treatment. Lithium, a clinical mood stabilizer for mental disorders, potently inhibits the activity of glycogen synthase kinase 3β...

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Detalles Bibliográficos
Autores principales:	Peng, Zhonglu, Ji, Zhengyu, Mei, Fang, Lu, Meiling, Ou, Yu, Cheng, Xiaodong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634073/ https://www.ncbi.nlm.nih.gov/pubmed/23626687 http://dx.doi.org/10.1371/journal.pone.0061457

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