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An Optical Super-Microscope for Far-field, Real-time Imaging Beyond the Diffraction Limit
Optical microscopy suffers from a fundamental resolution limitation arising from the diffractive nature of light. While current solutions to sub-diffraction optical microscopy involve combinations of near-field, non-linear and fine scanning operations, we hereby propose and demonstrate the optical s...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634104/ https://www.ncbi.nlm.nih.gov/pubmed/23612684 http://dx.doi.org/10.1038/srep01715 |
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author | Wong, Alex M. H. Eleftheriades, George V. |
author_facet | Wong, Alex M. H. Eleftheriades, George V. |
author_sort | Wong, Alex M. H. |
collection | PubMed |
description | Optical microscopy suffers from a fundamental resolution limitation arising from the diffractive nature of light. While current solutions to sub-diffraction optical microscopy involve combinations of near-field, non-linear and fine scanning operations, we hereby propose and demonstrate the optical super-microscope (OSM) – a superoscillation-based linear imaging system with far-field working and observation distances – which can image an object in real-time and with sub-diffraction resolution. With our proof-of-principle prototype we report a point spread function with a spot size clearly reduced from the diffraction limit, and demonstrate corresponding improvements in two-point resolution experiments. Harnessing a new understanding of superoscillations, based on antenna array theory, our OSM achieves far-field, sub-diffraction optical imaging of an object without the need for fine scanning, data post-processing or object pre-treatment. Hence the OSM can be used in a wide variety of imaging applications beyond the diffraction limit, including real-time imaging of moving objects. |
format | Online Article Text |
id | pubmed-3634104 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-36341042013-04-25 An Optical Super-Microscope for Far-field, Real-time Imaging Beyond the Diffraction Limit Wong, Alex M. H. Eleftheriades, George V. Sci Rep Article Optical microscopy suffers from a fundamental resolution limitation arising from the diffractive nature of light. While current solutions to sub-diffraction optical microscopy involve combinations of near-field, non-linear and fine scanning operations, we hereby propose and demonstrate the optical super-microscope (OSM) – a superoscillation-based linear imaging system with far-field working and observation distances – which can image an object in real-time and with sub-diffraction resolution. With our proof-of-principle prototype we report a point spread function with a spot size clearly reduced from the diffraction limit, and demonstrate corresponding improvements in two-point resolution experiments. Harnessing a new understanding of superoscillations, based on antenna array theory, our OSM achieves far-field, sub-diffraction optical imaging of an object without the need for fine scanning, data post-processing or object pre-treatment. Hence the OSM can be used in a wide variety of imaging applications beyond the diffraction limit, including real-time imaging of moving objects. Nature Publishing Group 2013-04-24 /pmc/articles/PMC3634104/ /pubmed/23612684 http://dx.doi.org/10.1038/srep01715 Text en Copyright © 2013, Macmillan Publishers Limited. All rights reserved http://creativecommons.org/licenses/by-nc-nd/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/ |
spellingShingle | Article Wong, Alex M. H. Eleftheriades, George V. An Optical Super-Microscope for Far-field, Real-time Imaging Beyond the Diffraction Limit |
title | An Optical Super-Microscope for Far-field, Real-time Imaging Beyond the Diffraction Limit |
title_full | An Optical Super-Microscope for Far-field, Real-time Imaging Beyond the Diffraction Limit |
title_fullStr | An Optical Super-Microscope for Far-field, Real-time Imaging Beyond the Diffraction Limit |
title_full_unstemmed | An Optical Super-Microscope for Far-field, Real-time Imaging Beyond the Diffraction Limit |
title_short | An Optical Super-Microscope for Far-field, Real-time Imaging Beyond the Diffraction Limit |
title_sort | optical super-microscope for far-field, real-time imaging beyond the diffraction limit |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634104/ https://www.ncbi.nlm.nih.gov/pubmed/23612684 http://dx.doi.org/10.1038/srep01715 |
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