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An Optical Super-Microscope for Far-field, Real-time Imaging Beyond the Diffraction Limit

Optical microscopy suffers from a fundamental resolution limitation arising from the diffractive nature of light. While current solutions to sub-diffraction optical microscopy involve combinations of near-field, non-linear and fine scanning operations, we hereby propose and demonstrate the optical s...

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Detalles Bibliográficos
Autores principales: Wong, Alex M. H., Eleftheriades, George V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634104/
https://www.ncbi.nlm.nih.gov/pubmed/23612684
http://dx.doi.org/10.1038/srep01715
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author Wong, Alex M. H.
Eleftheriades, George V.
author_facet Wong, Alex M. H.
Eleftheriades, George V.
author_sort Wong, Alex M. H.
collection PubMed
description Optical microscopy suffers from a fundamental resolution limitation arising from the diffractive nature of light. While current solutions to sub-diffraction optical microscopy involve combinations of near-field, non-linear and fine scanning operations, we hereby propose and demonstrate the optical super-microscope (OSM) – a superoscillation-based linear imaging system with far-field working and observation distances – which can image an object in real-time and with sub-diffraction resolution. With our proof-of-principle prototype we report a point spread function with a spot size clearly reduced from the diffraction limit, and demonstrate corresponding improvements in two-point resolution experiments. Harnessing a new understanding of superoscillations, based on antenna array theory, our OSM achieves far-field, sub-diffraction optical imaging of an object without the need for fine scanning, data post-processing or object pre-treatment. Hence the OSM can be used in a wide variety of imaging applications beyond the diffraction limit, including real-time imaging of moving objects.
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spelling pubmed-36341042013-04-25 An Optical Super-Microscope for Far-field, Real-time Imaging Beyond the Diffraction Limit Wong, Alex M. H. Eleftheriades, George V. Sci Rep Article Optical microscopy suffers from a fundamental resolution limitation arising from the diffractive nature of light. While current solutions to sub-diffraction optical microscopy involve combinations of near-field, non-linear and fine scanning operations, we hereby propose and demonstrate the optical super-microscope (OSM) – a superoscillation-based linear imaging system with far-field working and observation distances – which can image an object in real-time and with sub-diffraction resolution. With our proof-of-principle prototype we report a point spread function with a spot size clearly reduced from the diffraction limit, and demonstrate corresponding improvements in two-point resolution experiments. Harnessing a new understanding of superoscillations, based on antenna array theory, our OSM achieves far-field, sub-diffraction optical imaging of an object without the need for fine scanning, data post-processing or object pre-treatment. Hence the OSM can be used in a wide variety of imaging applications beyond the diffraction limit, including real-time imaging of moving objects. Nature Publishing Group 2013-04-24 /pmc/articles/PMC3634104/ /pubmed/23612684 http://dx.doi.org/10.1038/srep01715 Text en Copyright © 2013, Macmillan Publishers Limited. All rights reserved http://creativecommons.org/licenses/by-nc-nd/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/
spellingShingle Article
Wong, Alex M. H.
Eleftheriades, George V.
An Optical Super-Microscope for Far-field, Real-time Imaging Beyond the Diffraction Limit
title An Optical Super-Microscope for Far-field, Real-time Imaging Beyond the Diffraction Limit
title_full An Optical Super-Microscope for Far-field, Real-time Imaging Beyond the Diffraction Limit
title_fullStr An Optical Super-Microscope for Far-field, Real-time Imaging Beyond the Diffraction Limit
title_full_unstemmed An Optical Super-Microscope for Far-field, Real-time Imaging Beyond the Diffraction Limit
title_short An Optical Super-Microscope for Far-field, Real-time Imaging Beyond the Diffraction Limit
title_sort optical super-microscope for far-field, real-time imaging beyond the diffraction limit
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634104/
https://www.ncbi.nlm.nih.gov/pubmed/23612684
http://dx.doi.org/10.1038/srep01715
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