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Pharmacology and clinical potential of guanylyl cyclase C agonists in the treatment of ulcerative colitis
Agonists of the transmembrane intestinal receptor guanylyl cyclase C (GCC) have recently attracted interest as promising human therapeutics. Peptide ligands that can specifically induce GCC signaling in the intestine include endogenous hormones guanylin and uroguanylin, diarrheagenic bacterial enter...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634396/ https://www.ncbi.nlm.nih.gov/pubmed/23637522 http://dx.doi.org/10.2147/DDDT.S32252 |