Cargando…
Tumor Suppressor Role of Notch1 and Raf-1 Signaling in Medullary Thyroid Cancer Cells
There is a growing body of literature suggesting that signaling based therapy might be a potential approach for medullary thyroid cancer (MTC). In this review we focus on the tumor suppressor role of Notch1 and Raf-1 signaling in MTC. Interestingly these two pathways are minimally active or absent i...
Autores principales: | Kunnimalaiyaan, Muthusamy, Haymart, Megan R., Chen, Herbert |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Libertas Academica
2007
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634621/ https://www.ncbi.nlm.nih.gov/pubmed/23641144 |
Ejemplares similares
-
Medullary Thyroid Carcinoma: Targeted Therapies and Future Directions
por: Pinchot, Scott N., et al.
Publicado: (2009) -
Xanthohumol Inhibits Notch Signaling and Induces Apoptosis in Hepatocellular Carcinoma
por: Kunnimalaiyaan, Selvi, et al.
Publicado: (2015) -
Sprouty1 is a candidate tumor suppressor gene in medullary thyroid carcinoma
por: Macià, Anna, et al.
Publicado: (2011) -
A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis
por: Jeric, Ines, et al.
Publicado: (2016) -
Synergistic antitumour activity of RAF265 and ZSTK474 on human TT medullary thyroid cancer cells
por: Bertazza, Loris, et al.
Publicado: (2015)