H. pylori virulence factor CagA increases intestinal cell proliferation by Wnt pathway activation in a transgenic zebrafish model

Infection with Helicobacter pylori is a major risk factor for the development of gastric cancer, and infection with strains carrying the virulence factor CagA significantly increases this risk. To investigate the mechanisms by which CagA promotes carcinogenesis, we generated transgenic zebrafish exp...

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Detalles Bibliográficos
Autores principales: Neal, James T., Peterson, Tracy S., Kent, Michael L., Guillemin, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634662/
https://www.ncbi.nlm.nih.gov/pubmed/23471915
http://dx.doi.org/10.1242/dmm.011163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634662/
https://www.ncbi.nlm.nih.gov/pubmed/23471915
http://dx.doi.org/10.1242/dmm.011163

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