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An entirely automated method to score DSS-induced colitis in mice by digital image analysis of pathology slides

The DSS (dextran sulfate sodium) model of colitis is a mouse model of inflammatory bowel disease. Microscopic symptoms include loss of crypt cells from the gut lining and infiltration of inflammatory cells into the colon. An experienced pathologist requires several hours per study to score histologi...

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Detalles Bibliográficos
Autores principales: Kozlowski, Cleopatra, Jeet, Surinder, Beyer, Joseph, Guerrero, Steve, Lesch, Justin, Wang, Xiaoting, DeVoss, Jason, Diehl, Lauri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634668/
https://www.ncbi.nlm.nih.gov/pubmed/23580198
http://dx.doi.org/10.1242/dmm.011759