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Genetic Variants and Increased Expression of Parascaris equorum P-glycoprotein-11 in Populations with Decreased Ivermectin Susceptibility

Macrocyclic lactones (MLs) represent the major drug class for control of parasitic infections in humans and animals. However, recently reports of treatment failures became more frequent. In addition to human and ruminant parasitic nematodes this also is the case for the horse-nematode Parascaris equ...

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Detalles Bibliográficos
Autores principales: Janssen, I. Jana I., Krücken, Jürgen, Demeler, Janina, Basiaga, Marta, Kornaś, Sławomir, von Samson-Himmelstjerna, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634834/
https://www.ncbi.nlm.nih.gov/pubmed/23637871
http://dx.doi.org/10.1371/journal.pone.0061635