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Genetic Variants and Increased Expression of Parascaris equorum P-glycoprotein-11 in Populations with Decreased Ivermectin Susceptibility
Macrocyclic lactones (MLs) represent the major drug class for control of parasitic infections in humans and animals. However, recently reports of treatment failures became more frequent. In addition to human and ruminant parasitic nematodes this also is the case for the horse-nematode Parascaris equ...
Autores principales: | Janssen, I. Jana I., Krücken, Jürgen, Demeler, Janina, Basiaga, Marta, Kornaś, Sławomir, von Samson-Himmelstjerna, Georg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634834/ https://www.ncbi.nlm.nih.gov/pubmed/23637871 http://dx.doi.org/10.1371/journal.pone.0061635 |
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