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Permeabilization of the Blood-Brain Barrier via Mucosal Engrafting: Implications for Drug Delivery to the Brain
Utilization of neuropharmaceuticals for central nervous system(CNS) disease is highly limited due to the blood-brain barrier(BBB) which restricts molecules larger than 500Da from reaching the CNS. The development of a reliable method to bypass the BBB would represent an enormous advance in neurophar...
Autores principales: | Bleier, Benjamin S., Kohman, Richie E., Feldman, Rachel E., Ramanlal, Shreshtha, Han, Xue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634848/ https://www.ncbi.nlm.nih.gov/pubmed/23637885 http://dx.doi.org/10.1371/journal.pone.0061694 |
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