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Optimizing parametrial aperture design utilizing HDR brachytherapy isodose distribution

Treatment of cervical cancer includes combination of external beam radiation therapy (EBRT) and brachytherapy (BRT). Traditionally, coronal images displaying dose distribution from a ring and tandem (R&T) implant aid in construction of parametrial boost fields. This research aimed to evaluate a...

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Detalles Bibliográficos
Autores principales: Chapman, Katherine L., Ohri, Nitin, Showalter, Timothy N., Doyle, Laura A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635048/
https://www.ncbi.nlm.nih.gov/pubmed/23634156
http://dx.doi.org/10.5114/jcb.2013.34341
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author Chapman, Katherine L.
Ohri, Nitin
Showalter, Timothy N.
Doyle, Laura A.
author_facet Chapman, Katherine L.
Ohri, Nitin
Showalter, Timothy N.
Doyle, Laura A.
author_sort Chapman, Katherine L.
collection PubMed
description Treatment of cervical cancer includes combination of external beam radiation therapy (EBRT) and brachytherapy (BRT). Traditionally, coronal images displaying dose distribution from a ring and tandem (R&T) implant aid in construction of parametrial boost fields. This research aimed to evaluate a method of shaping parametrial fields utilizing contours created from the high-dose-rate (HDR) BRT dose distribution. Eleven patients receiving HDR-BRT via R&T were identified. The BRT and EBRT CT scans were sent to FocalSim (v4.62)(®) and fused based on bony anatomy. The contour of the HDR isodose line was transferred to the EBRT scan. The EBRT scan was sent to CMS-XIO (v4.62)(®) for planning. This process provides an automated, potentially more accurate method of matching the medial parametrial border to the HDR dose distribution. This allows for a 3D-view of dose from HDR-BRT for clinical decision-making, utilizes a paperless process and saves time over the traditional technique.
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spelling pubmed-36350482013-04-30 Optimizing parametrial aperture design utilizing HDR brachytherapy isodose distribution Chapman, Katherine L. Ohri, Nitin Showalter, Timothy N. Doyle, Laura A. J Contemp Brachytherapy Original Paper Treatment of cervical cancer includes combination of external beam radiation therapy (EBRT) and brachytherapy (BRT). Traditionally, coronal images displaying dose distribution from a ring and tandem (R&T) implant aid in construction of parametrial boost fields. This research aimed to evaluate a method of shaping parametrial fields utilizing contours created from the high-dose-rate (HDR) BRT dose distribution. Eleven patients receiving HDR-BRT via R&T were identified. The BRT and EBRT CT scans were sent to FocalSim (v4.62)(®) and fused based on bony anatomy. The contour of the HDR isodose line was transferred to the EBRT scan. The EBRT scan was sent to CMS-XIO (v4.62)(®) for planning. This process provides an automated, potentially more accurate method of matching the medial parametrial border to the HDR dose distribution. This allows for a 3D-view of dose from HDR-BRT for clinical decision-making, utilizes a paperless process and saves time over the traditional technique. Termedia Publishing House 2013-03-29 2013-03 /pmc/articles/PMC3635048/ /pubmed/23634156 http://dx.doi.org/10.5114/jcb.2013.34341 Text en Copyright © 2013 Termedia http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Paper
Chapman, Katherine L.
Ohri, Nitin
Showalter, Timothy N.
Doyle, Laura A.
Optimizing parametrial aperture design utilizing HDR brachytherapy isodose distribution
title Optimizing parametrial aperture design utilizing HDR brachytherapy isodose distribution
title_full Optimizing parametrial aperture design utilizing HDR brachytherapy isodose distribution
title_fullStr Optimizing parametrial aperture design utilizing HDR brachytherapy isodose distribution
title_full_unstemmed Optimizing parametrial aperture design utilizing HDR brachytherapy isodose distribution
title_short Optimizing parametrial aperture design utilizing HDR brachytherapy isodose distribution
title_sort optimizing parametrial aperture design utilizing hdr brachytherapy isodose distribution
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635048/
https://www.ncbi.nlm.nih.gov/pubmed/23634156
http://dx.doi.org/10.5114/jcb.2013.34341
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