A Whole Cell Pathway Screen Reveals Seven Novel Chemosensitizers to Combat Chloroquine Resistant Malaria

Due to the widespread prevalence of resistant parasites, chloroquine (CQ) was removed from front-line antimalarial chemotherapy in the 1990s despite its initial promise of disease eradication. Since then, resistance-conferring mutations have been identified in transporters such as the PfCRT, that al...

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Detalles Bibliográficos
Autores principales: Ch'ng, Jun-Hong, Mok, Sachel, Bozdech, Zbynek, Lear, Martin James, Boudhar, Aicha, Russell, Bruce, Nosten, Francois, Tan, Kevin Shyong-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635055/
https://www.ncbi.nlm.nih.gov/pubmed/23615863
http://dx.doi.org/10.1038/srep01734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635055/
https://www.ncbi.nlm.nih.gov/pubmed/23615863
http://dx.doi.org/10.1038/srep01734

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