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PICK1 and ICA69 Control Insulin Granule Trafficking and Their Deficiencies Lead to Impaired Glucose Tolerance

Diabetes is a metabolic disorder characterized by hyperglycemia. Insulin, which is secreted by pancreatic beta cells, is recognized as the critical regulator of blood glucose, but the molecular machinery responsible for insulin trafficking remains poorly defined. In particular, the roles of cytosoli...

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Detalles Bibliográficos
Autores principales:	Cao, Mian, Mao, Zhuo, Kam, Chuen, Xiao, Nan, Cao, Xiaoxing, Shen, Chong, Cheng, Kenneth K. Y., Xu, Aimin, Lee, Kwong-Man, Jiang, Liwen, Xia, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635858/ https://www.ncbi.nlm.nih.gov/pubmed/23630453 http://dx.doi.org/10.1371/journal.pbio.1001541

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