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RanBP2/Nup358 Potentiates the Translation of a Subset of mRNAs Encoding Secretory Proteins
In higher eukaryotes, most mRNAs that encode secreted or membrane-bound proteins contain elements that promote an alternative mRNA nuclear export (ALREX) pathway. Here we report that ALREX-promoting elements also potentiate translation in the presence of upstream nuclear factors. These RNA elements...
Autores principales: | Mahadevan, Kohila, Zhang, Hui, Akef, Abdalla, Cui, Xianying A., Gueroussov, Serge, Cenik, Can, Roth, Frederick P., Palazzo, Alexander F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635865/ https://www.ncbi.nlm.nih.gov/pubmed/23630457 http://dx.doi.org/10.1371/journal.pbio.1001545 |
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