Immunohistochemical detection of mutations in the epidermal growth factor receptor gene in lung adenocarcinomas using mutation-specific antibodies

BACKGROUND: The recent development of antibodies specific for the major hotspot mutations in the epidermal growth factor receptor (EGFR), L858R and E746_A750del, may provide an opportunity to use immunohistochemistry (IHC) as a screening test for EGFR gene mutations. This study was designed to optim...

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Detalles Bibliográficos
Autores principales: Xiong, Yan, Bai, Yun, Leong, Nufatt, Laughlin, Todd S, Rothberg, Paul G, Xu, Haodong, Nong, Lin, Zhao, Jing, Dong, Ying, Li, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635899/
https://www.ncbi.nlm.nih.gov/pubmed/23419122
http://dx.doi.org/10.1186/1746-1596-8-27

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