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Endogenous mammalian histone H3.3 exhibits chromatin-related functions during development

BACKGROUND: The histone variant H3.3 plays key roles in regulating chromatin states and transcription. However, the role of endogenous H3.3 in mammalian cells and during development has been less thoroughly investigated. To address this gap, we report the production and phenotypic analysis of mice a...

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Detalles Bibliográficos
Autores principales: Bush, Kelly M, Yuen, Benjamin TK, Barrilleaux, Bonnie L, Riggs, John W, O’Geen, Henriette, Cotterman, Rebecca F, Knoepfler, Paul S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635903/
https://www.ncbi.nlm.nih.gov/pubmed/23570311
http://dx.doi.org/10.1186/1756-8935-6-7