Timp1 interacts with beta-1 integrin and CD63 along melanoma genesis and confers anoikis resistance by activating PI3-K signaling pathway independently of Akt phosphorylation

BACKGROUND: Anoikis resistance is one of the abilities acquired along tumor progression. This characteristic is associated with metastasis development, since tumorigenic cells must survive independently of cell-matrix interactions in this process. In our laboratory, it was developed a murine melanoc...

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Detalles Bibliográficos
Autores principales: Toricelli, Mariana, Melo, Fabiana HM, Peres, Giovani B, Silva, Débora CP, Jasiulionis, Miriam G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635912/
https://www.ncbi.nlm.nih.gov/pubmed/23522389
http://dx.doi.org/10.1186/1476-4598-12-22

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