Quantifying the contribution of chromatin dynamics to stochastic gene expression reveals long, locus-dependent periods between transcriptional bursts

BACKGROUND: A number of studies have established that stochasticity in gene expression may play an important role in many biological phenomena. This therefore calls for further investigations to identify the molecular mechanisms at stake, in order to understand and manipulate cell-to-cell variabilit...

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Detalles Bibliográficos
Autores principales: Viñuelas, José, Kaneko, Gaël, Coulon, Antoine, Vallin, Elodie, Morin, Valérie, Mejia-Pous, Camila, Kupiec, Jean-Jacques, Beslon, Guillaume, Gandrillon, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635915/
https://www.ncbi.nlm.nih.gov/pubmed/23442824
http://dx.doi.org/10.1186/1741-7007-11-15

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