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Design and evaluation of Lumefantrine – Oleic acid self nanoemulsifying ionic complex for enhanced dissolution

BACKGROUND: Lumefantrine, an antimalarial molecule has very low and variable bioavailability owing to its extremely poor solubility in water. It is recommended to be taken with milk to enhance its solubility and bioavailability. The aim of present study was to develop a Self Nanoemulsifying Delivery...

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Detalles Bibliográficos
Autores principales: Patel, Ketan, Sarma, Vidur, Vavia, Pradeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635930/
https://www.ncbi.nlm.nih.gov/pubmed/23531442
http://dx.doi.org/10.1186/2008-2231-21-27