IL-1β Production through the NLRP3 Inflammasome by Hepatic Macrophages Links Hepatitis C Virus Infection with Liver Inflammation and Disease

Chronic hepatitis C virus (HCV) infection is a leading cause of liver disease. Liver inflammation underlies infection-induced fibrosis, cirrhosis and liver cancer but the processes that promote hepatic inflammation by HCV are not defined. We provide a systems biology analysis with multiple lines of...

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Detalles Bibliográficos
Autores principales: Negash, Amina A., Ramos, Hilario J., Crochet, Nanette, Lau, Daryl T. Y., Doehle, Brian, Papic, Neven, Delker, Don A., Jo, Juandy, Bertoletti, Antonio, Hagedorn, Curt H., Gale, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635973/
https://www.ncbi.nlm.nih.gov/pubmed/23633957
http://dx.doi.org/10.1371/journal.ppat.1003330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635973/
https://www.ncbi.nlm.nih.gov/pubmed/23633957
http://dx.doi.org/10.1371/journal.ppat.1003330

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