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Fragile X mental retardation protein and synaptic plasticity

Loss of the translational repressor FMRP causes Fragile X syndrome. In healthy neurons, FMRP modulates the local translation of numerous synaptic proteins. Synthesis of these proteins is required for the maintenance and regulation of long-lasting changes in synaptic strength. In this role as a trans...

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Detalles Bibliográficos
Autores principales:	Sidorov, Michael S, Auerbach, Benjamin D, Bear, Mark F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636002/ https://www.ncbi.nlm.nih.gov/pubmed/23566911 http://dx.doi.org/10.1186/1756-6606-6-15

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