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Phylogenetic analysis of the haemagglutinin gene of canine distemper virus strains detected from giant panda and raccoon dogs in China

BACKGROUND: Canine distemper virus (CDV) infects a variety of carnivores, including wild and domestic Canidae. In this study, we sequenced and phylogenetic analyses of the hemagglutinin (H) genes from eight canine distemper virus (CDV) isolates obtained from seven raccoon dogs (Nyctereutes procyonoi...

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Autores principales: Guo, Ling, Yang, Shao-lin, Wang, Cheng-dong, Hou, Rong, Chen, Shi-jie, Yang, Xiao-nong, Liu, Jie, Pan, Hai-bo, Hao, Zhong-xiang, Zhang, Man-li, Cao, San-jie, Yan, Qi-gui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636003/
https://www.ncbi.nlm.nih.gov/pubmed/23566727
http://dx.doi.org/10.1186/1743-422X-10-109
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author Guo, Ling
Yang, Shao-lin
Wang, Cheng-dong
Hou, Rong
Chen, Shi-jie
Yang, Xiao-nong
Liu, Jie
Pan, Hai-bo
Hao, Zhong-xiang
Zhang, Man-li
Cao, San-jie
Yan, Qi-gui
author_facet Guo, Ling
Yang, Shao-lin
Wang, Cheng-dong
Hou, Rong
Chen, Shi-jie
Yang, Xiao-nong
Liu, Jie
Pan, Hai-bo
Hao, Zhong-xiang
Zhang, Man-li
Cao, San-jie
Yan, Qi-gui
author_sort Guo, Ling
collection PubMed
description BACKGROUND: Canine distemper virus (CDV) infects a variety of carnivores, including wild and domestic Canidae. In this study, we sequenced and phylogenetic analyses of the hemagglutinin (H) genes from eight canine distemper virus (CDV) isolates obtained from seven raccoon dogs (Nyctereutes procyonoides) and a giant panda (Ailuropoda melanoleuca) in China. RESULTS: Phylogenetic analysis of the partial hemagglutinin gene sequences showed close clustering for geographic lineages, clearly distinct from vaccine strains and other wild-type foreign CDV strains, all the CDV strains were characterized as Asia-1 genotype and were highly similar to each other (91.5-99.8% nt and 94.4-99.8% aa). The giant panda and raccoon dogs all were 549Y on the HA protein in this study, irrespective of the host species. CONCLUSIONS: These findings enhance our knowledge of the genetic characteristics of Chinese CDV isolates, and may facilitate the development of effective strategies for monitoring and controlling CDV for wild canids and non-cainds in China.
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spelling pubmed-36360032013-04-26 Phylogenetic analysis of the haemagglutinin gene of canine distemper virus strains detected from giant panda and raccoon dogs in China Guo, Ling Yang, Shao-lin Wang, Cheng-dong Hou, Rong Chen, Shi-jie Yang, Xiao-nong Liu, Jie Pan, Hai-bo Hao, Zhong-xiang Zhang, Man-li Cao, San-jie Yan, Qi-gui Virol J Research BACKGROUND: Canine distemper virus (CDV) infects a variety of carnivores, including wild and domestic Canidae. In this study, we sequenced and phylogenetic analyses of the hemagglutinin (H) genes from eight canine distemper virus (CDV) isolates obtained from seven raccoon dogs (Nyctereutes procyonoides) and a giant panda (Ailuropoda melanoleuca) in China. RESULTS: Phylogenetic analysis of the partial hemagglutinin gene sequences showed close clustering for geographic lineages, clearly distinct from vaccine strains and other wild-type foreign CDV strains, all the CDV strains were characterized as Asia-1 genotype and were highly similar to each other (91.5-99.8% nt and 94.4-99.8% aa). The giant panda and raccoon dogs all were 549Y on the HA protein in this study, irrespective of the host species. CONCLUSIONS: These findings enhance our knowledge of the genetic characteristics of Chinese CDV isolates, and may facilitate the development of effective strategies for monitoring and controlling CDV for wild canids and non-cainds in China. BioMed Central 2013-04-08 /pmc/articles/PMC3636003/ /pubmed/23566727 http://dx.doi.org/10.1186/1743-422X-10-109 Text en Copyright © 2013 Guo et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Guo, Ling
Yang, Shao-lin
Wang, Cheng-dong
Hou, Rong
Chen, Shi-jie
Yang, Xiao-nong
Liu, Jie
Pan, Hai-bo
Hao, Zhong-xiang
Zhang, Man-li
Cao, San-jie
Yan, Qi-gui
Phylogenetic analysis of the haemagglutinin gene of canine distemper virus strains detected from giant panda and raccoon dogs in China
title Phylogenetic analysis of the haemagglutinin gene of canine distemper virus strains detected from giant panda and raccoon dogs in China
title_full Phylogenetic analysis of the haemagglutinin gene of canine distemper virus strains detected from giant panda and raccoon dogs in China
title_fullStr Phylogenetic analysis of the haemagglutinin gene of canine distemper virus strains detected from giant panda and raccoon dogs in China
title_full_unstemmed Phylogenetic analysis of the haemagglutinin gene of canine distemper virus strains detected from giant panda and raccoon dogs in China
title_short Phylogenetic analysis of the haemagglutinin gene of canine distemper virus strains detected from giant panda and raccoon dogs in China
title_sort phylogenetic analysis of the haemagglutinin gene of canine distemper virus strains detected from giant panda and raccoon dogs in china
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636003/
https://www.ncbi.nlm.nih.gov/pubmed/23566727
http://dx.doi.org/10.1186/1743-422X-10-109
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