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Determinants at the N- and C-termini of Gα(12) required for activation of Rho-mediated signaling

BACKGROUND: Heterotrimeric guanine nucleotide binding proteins of the G12/13 subfamily, which includes the α-subunits Gα(12) and Gα(13), stimulate the monomeric G protein RhoA through interaction with a distinct subset of Rho-specific guanine nucleotide exchange factors (RhoGEFs). The structural fea...

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Detalles Bibliográficos
Autores principales:	Ritchie, Benjamin J, Smolski, William C, Montgomery, Ellyn R, Fisher, Elizabeth S, Choi, Tina Y, Olson, Calla M, Foster, Lori A, Meigs, Thomas E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636079/ https://www.ncbi.nlm.nih.gov/pubmed/23531275 http://dx.doi.org/10.1186/1750-2187-8-3

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