Breakpoint Analysis of Transcriptional and Genomic Profiles Uncovers Novel Gene Fusions Spanning Multiple Human Cancer Types

Gene fusions, like BCR/ABL1 in chronic myelogenous leukemia, have long been recognized in hematologic and mesenchymal malignancies. The recent finding of gene fusions in prostate and lung cancers has motivated the search for pathogenic gene fusions in other malignancies. Here, we developed a “breakp...

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Detalles Bibliográficos
Autores principales: Giacomini, Craig P., Sun, Steven, Varma, Sushama, Shain, A. Hunter, Giacomini, Marilyn M., Balagtas, Jay, Sweeney, Robert T., Lai, Everett, Del Vecchio, Catherine A., Forster, Andrew D., Clarke, Nicole, Montgomery, Kelli D., Zhu, Shirley, Wong, Albert J., van de Rijn, Matt, West, Robert B., Pollack, Jonathan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636093/
https://www.ncbi.nlm.nih.gov/pubmed/23637631
http://dx.doi.org/10.1371/journal.pgen.1003464

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