Cargando…

Use of Natural Products as Chemical Library for Drug Discovery and Network Pharmacology

BACKGROUND: Natural products have been an important source of lead compounds for drug discovery. How to find and evaluate bioactive natural products is critical to the achievement of drug/lead discovery from natural products. METHODOLOGY: We collected 19,7201 natural products structures, reported bi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gu, Jiangyong, Gui, Yuanshen, Chen, Lirong, Yuan, Gu, Lu, Hui-Zhe, Xu, Xiaojie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636197/ https://www.ncbi.nlm.nih.gov/pubmed/23638153 http://dx.doi.org/10.1371/journal.pone.0062839

Ejemplares similares

CVDHD: a cardiovascular disease herbal database for drug discovery and network pharmacology
por: Gu, Jiangyong, et al.
Publicado: (2013)

A Drug-Target Network-Based Approach to Evaluate the Efficacy of Medicinal Plants for Type II Diabetes Mellitus
por: Gu, Jiangyong, et al.
Publicado: (2013)

Fragment Library of Natural Products and Compound Databases for Drug Discovery †
por: Chávez-Hernández, Ana L., et al.
Publicado: (2020)

Marine Natural Product Libraries for High-Throughput Screening and Rapid Drug Discovery
por: Bugni, Tim S., et al.
Publicado: (2008)

Diversity‐Oriented Synthesis of Natural‐Product‐like Libraries Containing a 3‐Methylbenzofuran Moiety for the Discovery of New Chemical Elicitors
por: He, Xingrui, et al.
Publicado: (2016)

Quantitative modeling of dose–response and drug combination based on pathway network
por: Gu, Jiangyong, et al.
Publicado: (2015)

Platelet Aggregation Pathway Network-Based Approach for Evaluating Compounds Efficacy
por: Gu, Jiangyong, et al.
Publicado: (2013)

High-Throughput Screening of Natural Product and Synthetic Molecule Libraries for Antibacterial Drug Discovery
por: Ayon, Navid J.
Publicado: (2023)

DIY Virtual Chemical Libraries - Novel Starting Points for Drug Discovery
por: Takács, Gergely, et al.
Publicado: (2023)

Assessing the Anti-inflammatory Mechanism of Reduning Injection by Network Pharmacology
por: Xie, Fuda, et al.
Publicado: (2020)

Pharmacological applications of natural peptide libraries
por: Koehbach, Johannes, et al.
Publicado: (2012)

Natural products and drug discovery
por: Newman, David J
Publicado: (2022)

Drug Discovery on Natural Products: From Ion Channels to nAChRs, from Nature to Libraries, from Analytics to Assays
por: Otvos, Reka A., et al.
Publicado: (2019)

Editorial: MSPP 34th scientific meeting: Pharmacological perspectives on natural products in drug discovery
por: Shaikh, Mohd. Farooq, et al.
Publicado: (2022)

Computational Approaches for the Discovery and Development of Pharmacologically Active Natural Products
por: Medina-Franco, José L.
Publicado: (2021)

Screen for New Antimicrobial Natural Products from the NCI Program for Natural Product Discovery Prefractionated Extract Library
por: Martínez-Fructuoso, Lucero, et al.
Publicado: (2023)

Quality not Quantity: The Role of Marine Natural Products in Drug Discovery and Reverse Chemical Proteomics
por: Piggott, Andrew M., et al.
Publicado: (2005)

Covalent Docking of Large Libraries for the Discovery of Chemical Probes
por: London, Nir, et al.
Publicado: (2014)

Generating Focused Molecule Libraries for Drug Discovery with Recurrent Neural Networks
por: Segler, Marwin H. S., et al.
Publicado: (2017)

Drug Discovery, CAM and Natural Products
por: Cooper, Edwin L.
Publicado: (2004)

Repositioning Natural Products in Drug Discovery
por: Rastelli, Giulio, et al.
Publicado: (2020)

Impact of library input on the hit discovery rate in DNA-encoded chemical library selections
por: Puglioli, Sara, et al.
Publicado: (2023)

Unraveling Plant Natural Chemical Diversity for Drug Discovery Purposes
por: Lautié, Emmanuelle, et al.
Publicado: (2020)

Multiscale Modeling of Drug-induced Effects of ReDuNing Injection on Human Disease: From Drug Molecules to Clinical Symptoms of Disease
por: Luo, Fang, et al.
Publicado: (2015)

Pharmacognosy: Science of natural products in drug discovery
por: Orhan, Ilkay Erdogan
Publicado: (2014)

Unlocking the potential of natural products in drug discovery
por: Wright, Gerard D.
Publicado: (2018)

Natural Products as Leads in Schistosome Drug Discovery
por: Neves, Bruno J., et al.
Publicado: (2015)

Cheminformatics in Natural Product‐based Drug Discovery
por: Chen, Ya, et al.
Publicado: (2020)

Natural products in drug discovery: advances and opportunities
por: Atanasov, Atanas G., et al.
Publicado: (2021)

Evolving paradigms for natural-product drug discovery
por: Cordell, Geoffrey A
Publicado: (2022)

Natural Products in Renal-Associated Drug Discovery
por: Wruck, Wasco, et al.
Publicado: (2023)

Toxins in Drug Discovery and Pharmacology
por: Peigneur, Steve, et al.
Publicado: (2018)

Natural Products for Drug Discovery in the 21st Century: Innovations for Novel Drug Discovery
por: Thomford, Nicholas Ekow, et al.
Publicado: (2018)

Discovery and resupply of pharmacologically active plant-derived natural products: A review
por: Atanasov, Atanas G., et al.
Publicado: (2015)

Generation of a Small Library of Natural Products Designed to Cover Chemical Space Inexpensively
por: O’Hagan, Steve, et al.
Publicado: (2019)

Building Natural Product Libraries Using Quantitative Clade-Based and Chemical Clustering Strategies
por: Anderson, Victoria M., et al.
Publicado: (2021)

Ultra-large chemical libraries for the discovery of high-affinity peptide binders
por: Quartararo, Anthony J., et al.
Publicado: (2020)

Correlating chemical diversity with taxonomic distance for discovery of natural products in myxobacteria
por: Hoffmann, Thomas, et al.
Publicado: (2018)

Fractionated Marine Invertebrate Extract Libraries for Drug Discovery
por: Bugni, Tim S., et al.
Publicado: (2008)

A diverse global fungal library for drug discovery
por: Niu, Guodong, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_27dk8q6nk6pu1sre31lhf2pu6s