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MicroRNA-22 increases senescence and activates cardiac fibroblasts in the aging heart
MicroRNAs (miRs) are small non- coding RNA molecules controlling a plethora of biological processes such as development, cellular survival and senescence. We here determined miRs differentially regulated during cardiac postnatal development and aging. Cardiac function, morphology and miR expression...
Autores principales: | Jazbutyte, Virginija, Fiedler, Jan, Kneitz, Susanne, Galuppo, Paolo, Just, Annette, Holzmann, Angelika, Bauersachs, Johann, Thum, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636396/ https://www.ncbi.nlm.nih.gov/pubmed/22538858 http://dx.doi.org/10.1007/s11357-012-9407-9 |
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