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Nogo-A Downregulation Improves Insulin Secretion in Mice

Type 2 diabetes (T2D) is characterized by β-cell dysfunction and the subsequent depletion of insulin production, usually in a context of increased peripheral insulin resistance. T2D patients are routinely treated with oral antidiabetic agents such as sulfonylureas or dipeptidyl peptidase-4 antagonis...

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Detalles Bibliográficos
Autores principales: Bonal, Claire B., Baronnier, Delphine E., Pot, Caroline, Benkhoucha, Mahdia, Schwab, Martin E., Lalive, Patrice H., Herrera, Pedro L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636604/
https://www.ncbi.nlm.nih.gov/pubmed/23274909
http://dx.doi.org/10.2337/db12-0949