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LKB1 Regulates Lipid Oxidation During Exercise Independently of AMPK

Lipid metabolism is important for health and insulin action, yet the fundamental process of regulating lipid metabolism during muscle contraction is incompletely understood. Here, we show that liver kinase B1 (LKB1) muscle-specific knockout (LKB1 MKO) mice display decreased fatty acid (FA) oxidation...

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Detalles Bibliográficos
Autores principales: Jeppesen, Jacob, Maarbjerg, Stine J., Jordy, Andreas B., Fritzen, Andreas M., Pehmøller, Christian, Sylow, Lykke, Serup, Annette Karen, Jessen, Niels, Thorsen, Kasper, Prats, Clara, Qvortrup, Klaus, Dyck, Jason R.B., Hunter, Roger W., Sakamoto, Kei, Thomson, David M., Schjerling, Peter, Wojtaszewski, Jørgen F.P., Richter, Erik A., Kiens, Bente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636614/
https://www.ncbi.nlm.nih.gov/pubmed/23349504
http://dx.doi.org/10.2337/db12-1160