Permanent Neonatal Diabetes in INS(C94Y) Transgenic Pigs

Mutations in the insulin (INS) gene may cause permanent neonatal diabetes mellitus (PNDM). Ins2 mutant mouse models provided important insights into the disease mechanisms of PNDM but have limitations for translational research. To establish a large animal model of PNDM, we generated INS(C94Y) trans...

Descripción completa

Detalles Bibliográficos
Autores principales: Renner, Simone, Braun-Reichhart, Christina, Blutke, Andreas, Herbach, Nadja, Emrich, Daniela, Streckel, Elisabeth, Wünsch, Annegret, Kessler, Barbara, Kurome, Mayuko, Bähr, Andrea, Klymiuk, Nikolai, Krebs, Stefan, Puk, Oliver, Nagashima, Hiroshi, Graw, Jochen, Blum, Helmut, Wanke, Ruediger, Wolf, Eckhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636654/
https://www.ncbi.nlm.nih.gov/pubmed/23274907
http://dx.doi.org/10.2337/db12-1065

Ejemplares similares

Ejemplares similares