Secondary Membranous Nephropathy Associated with Guillain-Barré Syndrome

Membranous nephropathy (MN) is one of the most common causes of nephrotic syndrome (NS) in adults. It may be primary, usually mediated by IgG4 anti-phospholipase A2 autoantibodies or secondary to various other conditions. Guillain- Barré syndrome (GBS) has been associated with MN, but a cause and ef...

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Autores principales: J. Filippone, Edward, Kanzaria, Mitul, Bell, Rodney, Newman, Eric, L. Farber, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2013
Materias:
Published online: April, 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636961/
https://www.ncbi.nlm.nih.gov/pubmed/23626596
http://dx.doi.org/10.1159/000350903
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author J. Filippone, Edward
Kanzaria, Mitul
Bell, Rodney
Newman, Eric
L. Farber, John
author_facet J. Filippone, Edward
Kanzaria, Mitul
Bell, Rodney
Newman, Eric
L. Farber, John
author_sort J. Filippone, Edward
collection PubMed
description Membranous nephropathy (MN) is one of the most common causes of nephrotic syndrome (NS) in adults. It may be primary, usually mediated by IgG4 anti-phospholipase A2 autoantibodies or secondary to various other conditions. Guillain- Barré syndrome (GBS) has been associated with MN, but a cause and effect relation has not been proven. We present a case of concurrent development of GBS and severe NS, with renal biopsy demonstrating MN. IgG4 stain was negative, indicating that most likely, the MN was secondary and probably caused by the underlying GBS.
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spelling pubmed-36369612013-04-26 Secondary Membranous Nephropathy Associated with Guillain-Barré Syndrome J. Filippone, Edward Kanzaria, Mitul Bell, Rodney Newman, Eric L. Farber, John Case Rep Nephrol Urol Published online: April, 2013 Membranous nephropathy (MN) is one of the most common causes of nephrotic syndrome (NS) in adults. It may be primary, usually mediated by IgG4 anti-phospholipase A2 autoantibodies or secondary to various other conditions. Guillain- Barré syndrome (GBS) has been associated with MN, but a cause and effect relation has not been proven. We present a case of concurrent development of GBS and severe NS, with renal biopsy demonstrating MN. IgG4 stain was negative, indicating that most likely, the MN was secondary and probably caused by the underlying GBS. S. Karger AG 2013-04-10 /pmc/articles/PMC3636961/ /pubmed/23626596 http://dx.doi.org/10.1159/000350903 Text en Copyright © 2013 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published online: April, 2013
J. Filippone, Edward
Kanzaria, Mitul
Bell, Rodney
Newman, Eric
L. Farber, John
Secondary Membranous Nephropathy Associated with Guillain-Barré Syndrome
title Secondary Membranous Nephropathy Associated with Guillain-Barré Syndrome
title_full Secondary Membranous Nephropathy Associated with Guillain-Barré Syndrome
title_fullStr Secondary Membranous Nephropathy Associated with Guillain-Barré Syndrome
title_full_unstemmed Secondary Membranous Nephropathy Associated with Guillain-Barré Syndrome
title_short Secondary Membranous Nephropathy Associated with Guillain-Barré Syndrome
title_sort secondary membranous nephropathy associated with guillain-barré syndrome
topic Published online: April, 2013
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636961/
https://www.ncbi.nlm.nih.gov/pubmed/23626596
http://dx.doi.org/10.1159/000350903
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