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Small molecular modulation of macrophage migration inhibitory factor in the hyperoxia-induced mouse model of bronchopulmonary dysplasia

BACKGROUND: The role and mechanism of action of MIF in bronchopulmonary dysplasia (BPD) are not known. We hypothesized that increased MIF signaling would ameliorate the pulmonary phenotype of BPD in the mouse lung. METHODS: We studied newborn wild type (WT), MIF knockout (MIFKO), and lung MIF transg...

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Detalles Bibliográficos
Autores principales: Sun, Huanxing, Choo-Wing, Rayman, Fan, Juan, Leng, Lin, Syed, Mansoor A, Hare, Alissa A, Jorgensen, William L, Bucala, Richard, Bhandari, Vineet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637059/
https://www.ncbi.nlm.nih.gov/pubmed/23448134
http://dx.doi.org/10.1186/1465-9921-14-27