New Insights into the Population Structure of Anopheles gambiae s.s. in the Gulf of Guinea Islands Revealed by Herves Transposable Elements

Transposable elements (TEs) are mobile portions of DNA that are able to replicate and spread in the genome of many organisms. TEs can be used as a means to insert transgenes in insects, being stably inherited throughout generations. Anopheles gambiae is the main vector of human malaria in Sub-Sahara...

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Autores principales: Salgueiro, Patrícia, Moreno, Marta, Simard, Frédéric, O'Brochta, David, Pinto, João
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637158/
https://www.ncbi.nlm.nih.gov/pubmed/23638171
http://dx.doi.org/10.1371/journal.pone.0062964
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author Salgueiro, Patrícia
Moreno, Marta
Simard, Frédéric
O'Brochta, David
Pinto, João
author_facet Salgueiro, Patrícia
Moreno, Marta
Simard, Frédéric
O'Brochta, David
Pinto, João
author_sort Salgueiro, Patrícia
collection PubMed
description Transposable elements (TEs) are mobile portions of DNA that are able to replicate and spread in the genome of many organisms. TEs can be used as a means to insert transgenes in insects, being stably inherited throughout generations. Anopheles gambiae is the main vector of human malaria in Sub-Saharan Africa. Given the extraordinary burden this disease imposes, the mosquito became a choice target for genetic control approaches with the purpose of reducing malaria transmission. In this study, we investigated the abundance and distribution of Herves TE in An. gambiae s.s. from Cameroon and four islands in the Gulf of Guinea, in order to determine their genetic structure. We have detected a population subdivision between Equatorial Guinea islands and the islands of São Tomé, Príncipe and mainland. This partitioning associates more with political rather than geographic boundaries, possibly reflecting different mainland source populations colonizing the islands.
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spelling pubmed-36371582013-05-01 New Insights into the Population Structure of Anopheles gambiae s.s. in the Gulf of Guinea Islands Revealed by Herves Transposable Elements Salgueiro, Patrícia Moreno, Marta Simard, Frédéric O'Brochta, David Pinto, João PLoS One Research Article Transposable elements (TEs) are mobile portions of DNA that are able to replicate and spread in the genome of many organisms. TEs can be used as a means to insert transgenes in insects, being stably inherited throughout generations. Anopheles gambiae is the main vector of human malaria in Sub-Saharan Africa. Given the extraordinary burden this disease imposes, the mosquito became a choice target for genetic control approaches with the purpose of reducing malaria transmission. In this study, we investigated the abundance and distribution of Herves TE in An. gambiae s.s. from Cameroon and four islands in the Gulf of Guinea, in order to determine their genetic structure. We have detected a population subdivision between Equatorial Guinea islands and the islands of São Tomé, Príncipe and mainland. This partitioning associates more with political rather than geographic boundaries, possibly reflecting different mainland source populations colonizing the islands. Public Library of Science 2013-04-26 /pmc/articles/PMC3637158/ /pubmed/23638171 http://dx.doi.org/10.1371/journal.pone.0062964 Text en © 2013 Salgueiro et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Salgueiro, Patrícia
Moreno, Marta
Simard, Frédéric
O'Brochta, David
Pinto, João
New Insights into the Population Structure of Anopheles gambiae s.s. in the Gulf of Guinea Islands Revealed by Herves Transposable Elements
title New Insights into the Population Structure of Anopheles gambiae s.s. in the Gulf of Guinea Islands Revealed by Herves Transposable Elements
title_full New Insights into the Population Structure of Anopheles gambiae s.s. in the Gulf of Guinea Islands Revealed by Herves Transposable Elements
title_fullStr New Insights into the Population Structure of Anopheles gambiae s.s. in the Gulf of Guinea Islands Revealed by Herves Transposable Elements
title_full_unstemmed New Insights into the Population Structure of Anopheles gambiae s.s. in the Gulf of Guinea Islands Revealed by Herves Transposable Elements
title_short New Insights into the Population Structure of Anopheles gambiae s.s. in the Gulf of Guinea Islands Revealed by Herves Transposable Elements
title_sort new insights into the population structure of anopheles gambiae s.s. in the gulf of guinea islands revealed by herves transposable elements
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637158/
https://www.ncbi.nlm.nih.gov/pubmed/23638171
http://dx.doi.org/10.1371/journal.pone.0062964
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