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Defective Lung Macrophage Function in Lung Cancer±Chronic Obstructive Pulmonary Disease (COPD/Emphysema)-Mediated by Cancer Cell Production of PGE2?

In chronic obstructive pulmonary disease (COPD/emphysema) we have shown a reduced ability of lung and alveolar (AM) macrophages to phagocytose apoptotic cells (defective ‘efferocytosis’), associated with evidence of secondary cellular necrosis and a resultant inflammatory response in the airway. It...

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Detalles Bibliográficos
Autores principales:	Dehle, Francis C., Mukaro, Violet R., Jurisevic, Craig, Moffat, David, Ahern, Jessica, Hodge, Greg, Jersmann, Hubertus, Reynolds, Paul N., Hodge, Sandra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637201/ https://www.ncbi.nlm.nih.gov/pubmed/23637858 http://dx.doi.org/10.1371/journal.pone.0061573

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