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Structural Basis of the Induced-Fit Mechanism of 1,4-Dihydroxy-2-Naphthoyl Coenzyme A Synthase from the Crotonase Fold Superfamily

1, 4-Dihydroxy-2-naphthoyl coenzyme A (DHNA-CoA) synthase is a typical crotonase fold enzyme with an implicated role of conformational changes in catalysis. We have identified these conformational changes by determining the structures of its Escherichia coli and Synechocystis sp. PCC6803 orthologues...

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Detalles Bibliográficos
Autores principales: Sun, Yueru, Song, Haigang, Li, Jie, Li, Yan, Jiang, Ming, Zhou, Jiahai, Guo, Zhihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637252/
https://www.ncbi.nlm.nih.gov/pubmed/23658663
http://dx.doi.org/10.1371/journal.pone.0063095