Deficiency of ADAMTS-13 in pediatric patients with severe sepsis and impact on in-hospital mortality

BACKGROUND: The enzyme involved in regulating the size of vWF (von Willebrand factor) in plasma is ADAMTS-13 (A disintegrin and metalloprotease with thrombospondin type-1 motives). Deficient proteolysis of ULvWF (ultra large von Willebrand factor) due to reduced ADAMTS-13 activity results in dissemi...

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Detalles Bibliográficos
Autores principales: Karim, Farheen, Adil, Salman Naseem, Afaq, Bushra, ul Haq, Anwar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637410/
https://www.ncbi.nlm.nih.gov/pubmed/23537039
http://dx.doi.org/10.1186/1471-2431-13-44

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