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ST6Gal-I sialyltransferase confers cisplatin resistance in ovarian tumor cells

BACKGROUND: Platinum drugs, including cisplatin, are a frontline therapeutic in ovarian cancer treatment and acquired resistance to these agents is a major contributor to ovarian cancer morbidity and mortality. In this study a novel glycosylation-dependent mechanism for cisplatin resistance is descr...

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Detalles Bibliográficos
Autores principales:	Schultz, Matthew J, Swindall, Amanda F, Wright, John W, Sztul, Elizabeth S, Landen, Charles N, Bellis, Susan L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637436/ https://www.ncbi.nlm.nih.gov/pubmed/23578204 http://dx.doi.org/10.1186/1757-2215-6-25

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