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Embryonic Stem Cells Are Redirected to Non-Tumorigenic Epithelial Cell Fate by Interaction with the Mammary Microenvironment

Experiments were conducted to redirect mouse Embryonic Stem (ES) cells from a tumorigenic phenotype to a normal mammary epithelial phenotype in vivo. Mixing LacZ-labeled ES cells with normal mouse mammary epithelial cells at ratios of 1∶5 and 1∶50 in phosphate buffered saline and immediately inocula...

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Detalles Bibliográficos
Autores principales:	Boulanger, Corinne A., Bruno, Robert D., Mack, David L., Gonzales, Monica, Castro, Nadia P., Salomon, David S., Smith, Gilbert H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637449/ https://www.ncbi.nlm.nih.gov/pubmed/23637952 http://dx.doi.org/10.1371/journal.pone.0062019

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